BCCM/IHEM publications


Becker P, Normand AC, Vanantwerpen G, Vanrobaeys M, Haesendonck R, Vercammen F, Stubbe D, Piarroux R, Hendrickx M (2018). Identification of fungal isolates by MALDI-TOF mass spectrometry in the veterinary practice: validation of a web application. Journal of Veterinary Diagnostic Investigation, in press.

D’hooge E, Becker P, Stubbe D, Normand AC, Piarroux P, Hendrickx M (2018). Black aspergilli: a remaining challenge in fungal taxonomy? Medical Mycology, in press.

Goemaere B, Lagrou K, Spriet I, Hendrickx M, Becker P (2018). Clonal spread of Candida glabrata bloodstream isolates and fluconazole resistance affected by prolonged exposure: a 12-year single-center study in Belgium. Antimicrobial Agents and Chemotherapy 62(8): e00591-18.

Goemaere B, Becker P, Van Wijngaerden E, Maertens J, Spriet I, Hendrickx M, Lagrou K (2018). Increasing candidemia incidence from 2004 to 2015 with a shift in epidemiology in patients pre-exposed to antifungals. Mycoses 67: 127-133.

De Crop E, Hampe F, Wisitrassameewong K, Stubbe D, Nuytinck J, Verbeken A (2018). Novel diversity in Lactifluus section Gerardii from Asia: five new species with pleurotoid or small agaricoid basidiocarps. Mycologia 110: 962-984.

Dupont D, Normand AC, Persat F, Hendrickx M, Piarroux R, Wallon M (2018). Comparison of matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) systems for the identification of moulds in the routine microbiology laboratory. Clinical Microbiology and Infection, in press.

Normand AC, Packeu A, Cassagne C, Hendrickx M, Ranque S, Piarroux R (2018). Nucleotide Sequence Database Comparison for Routine Dermatophyte Identification by Internal Transcribed Spacer 2 Genetic Region DNA Barcoding. Journal of Clinical Microbiology 56(5), e00046-18.

Stein M, Tran V, Nichol KA, Lagacé-Wiens P, Pieroni P, Adam HJ, Turenne C, Walkty AJ, Normand AC, Hendrickx M, Piarroux R, Karlowsky JA (2018). Evaluation of three MALDI-TOF mass spectrometry libraries for the identification of filamentous fungi in three clinical microbiology laboratories in Manitoba, Canada. Mycoses 61(10):743-753.



Normand AC, Becker P, Gabriel F, Cassagne C, Accoceberry I, Gari-Toussaint M, Hasseine L, De Geyter D, Pierard D, Surmont I, Djenad F, Donnadieu JL, Piarroux M, Ranque S, Hendrickx M, Piarroux R (2017). Online identification of fungi using MALDI-TOF mass spectrometry: validation of a new web application. Journal of Clinical Microbiology 55: 2661-2670.

Normand AC, Cassagne C, Gautier M, Becker P, Ranque S, Hendrickx M, Piarroux R (2017). Decision criteria for MALDI-TOF MS-based identification of filamentous fungi using in-house reference databases. BMC Microbiology 17: 25.

de Hoog GS, Dukik K, Monod M, Packeu A, Stubbe D, Hendrickx M, Kupsch C, Stielow JB, Freeke J, Göker M, Rezaei-Matehkolaei A, Mirhendi H, Gräser Y. Toward a Novel Multilocus Phylogenetic Taxonomy for the Dermatophytes. Mycopathologia 182: 5-31.

De Crop E, Nuytinck J, Van de Putte K, Wisitrassameewong K, Hackel J, Stubbe D, Hyde KD, Roy M, Halling RE, Moreau EA, Eberhardt U, Verbeken A (2017). A multi-gene phylogeny of Lactifluus (Basidiomycota, Ryssulales) translated into a new infrageneric classification of the genus. Persoonia: Molecular Phylogeny and Evolution of Fungi 38: 58-80.



Wisitrassameewong K, Looney BP, Le HT, De Crop E, Das K, Van de Putte K, Eberhardt u, Jiayu G, Stubbe D, Hyde KD, Verbeken A, Nuytinck J (2016). Lactarius subgenus Russularia (Basidiomycota, Russulales): novel Asian specias, worldwide phylogeny and evolutionary relationships. Fungal Biology 120: 1554-1581.

Triest D, Piérard D, De Cremer K, Hendrickx M (2016). Fusarium musae infected banana fruits as potential source of human fusariosis: may occur more frequently than we might think and hypotheses about infection. Communicative & Integrative Biology 9(2): e1162934.

Nyazika TK, Hagen F, Machiridza T, Kutepa M, Masanganise F, Hendrickx M, Boekhout T, Magombei-Majinjiwa T, Siziba N, Chin'ombe N, Mateveke K,  Meis JF, Robertson VJ (2016). Cryptococcus neoformans population diversity and clinical outcomes of HIV-associated cryptococcal meningitis patients in Zimbabwe. Journal of Medical Microbiology 65: 1281-1288.

Gautier M, Normand AC, L'Ollivier C, Cassagne C, Reynaud-Gaubert M, Dubus JC, Brégeon F, Hendrickx M, Gomez C , Ranque C, Piarroux R (2016). Aspergillus tubingensis : a major filamentous fungus found in the airways of patients with lung disease. Medical Mycology 54 (5): 459-470.



Becker P, Stubbe D, Claessens J, Roesems S, Bastin Y, Planard C, Cassagne C, Piarroux R, Hendrickx M (2015). Quality control in culture collections: confirming identity of filamentous fungi by MALDI-TOF MS. Mycoscience 56: 273-279.

Triest D, Stubbe D, De Cremer K, Piérard D, Detandt M, Hendrickx M (2015). Banana infecting fungus, Fusarium musae, is also an opportunistic human pathogen: are bananas potential carriers and source of fusariosis? Mycologia 107: 46-53.

Triest D, Stubbe D, De Cremer K, Piérard D, Normand AC, Piarroux R, Detandt M, Hendrickx M (2015). Use of MALDI-TOF MS for the identification of moulds of the Fusarium genus. Journal of Clinical Microbiology 53(2): 465-476.

Dhieb C, Normand AC, Al-Jasiri M, Chaker E, El Euch D, Hendrickx M, Sadfi N, Piarroux R, Ranque S (2015). MALDI-TOF typing highlights geographical and fluconazole resistance clusters in Candida glabrata. Medical Mycology 53(5):462-9.

Dhieb C, Normand AC, L’Ollivier C, Avellan-Gauthier M, Vranckx K, El Euch D, Hendrickx M, Sadfi N, Piarroux R, Ranque S (2015). Comparison of MALDI TOF Mass Spectra with Microsatellite Length Polymorfisms in Candida albicans. Journal of Mass Spectrometry 50(2): 371-377.

Iriny L (…Dirk S, Hendrickx M…) et al. (2015). Establishment of a quality controlled ISHAM-ITS reference database for human/animal pathogenic fungi – the value of the ITS region as official fungal barcode. Medical Mycology 53(4):313-37.

Al-Hatmi AMS, Normand AC, van Diepeningen AD, Hendrickx M, de Hoog GS, Piarroux R (2015). Rapid species-level identification of opportunists in the Fusarium fujikuroi species complex using MALDI-TOF mass spectrometry. Future Microbiology 10(12): 1939-1952.



Gautier M, Ranque S, Normand AC, Becker P, Packeu A, Cassagne C, L’Ollivier C, Hendrickx M, Piarroux R (2014). MALDI-TOF mass spectrometry: revolutionizing clinical laboratory diagnosis of mould infections Clinical Microbiology and Infection, doi: 10.1111/1469-0691.12750.

Becker P, De Bel A, Martiny D, Ranque S, Piarroux R, Cassagne C, Detandt M, Hendrickx M (2014). Identification of filamentous fungi isolates by MALDI-TOF mass spectrometry: clinical evaluation of an extended reference spectra library. Medical Mycology 52: 826-834.

Packeu A, De Bel A, L’Ollivier C, Ranque S, Detandt M, Hendrickx M (2014). Fast and accurate identification of dermatophytes by MALDI-TOF mass spectrometry: validation in the clinical lab. Journal of Clinical Microbiology 52(9): 3440-3443.

Ranque S, Normand AC, Cassagne C, Murat JB, Bourgeois N, Dalle F, Gari-Toussaint M, Fourquet P, Hendrickx M, Piarroux R (2014). MALDI-TOF mass spectrometry identification of filamentous fungi in the clinical laboratory. Mycoses 57 (3): 135–140.



Savini, V., Hendrickx, M., Sisti, M., Masciarelli, G., Favaro, M., fontana, C., Pitzurra, L., Arzeni, D., Astolfi, D., Catavitello, C., Polilli, E., Farina, C., Fazii, P., D'antonio, D., and Stubbe, D., (2013). An atypical, pigment-producing Metschnikowia strain from a leukaemia patient. Med Mycol 51, 438-443.

Beguin, H., Goens, K., Hendrickx, M., Planard, C., Stubbe, D., and Detandt, M., 2013. Is Trichophyton simii endemic to the Indian subcontinent? Med Mycol 51, 444-448.

L'ollivier, C., Cassagne, C., Normand, A.C., Bouchara, J.P., Contet-Audonneau, N., Hendrickx, M., Fourquet, P., Coulibaly, O., Piarroux, R., and Ranque, S., (2013). A MALDI-TOF MS procedure for clinical dermatophyte species identification in the routine laboratory. Med Mycol 51, 713-720.

Packeu, A., Hendrickx, M., Beguin, H., Martiny, D., Vandenberg, O., and Detandt, M., (2013). Identification of the Trichophyton mentagrophytes complex species using MALDI-TOF mass spectrometry. Med Mycol 51, 580-585.



Stubbe, D., Wang, X.H., and Verbeken, A., 2012. New combinations in Lactifluus. 2. L. subg. Gerardii. Mycotaxon 119, 483-485.

Beguin, H., Pyck, N., and Detandt, M., 2012. Tritirachium, a hyphomycetous genus belonging to the Basidiomycota. Nova Hedwigia 94, 139-152.

Wang, X.H., Stubbe, D., and Verbeken, A., 2012. Lactifluus parvigerardii sp. nov., a new link towards the pleurotoid habit in Lactifluus subgen. Gerardii (Russulaceae, Russulales). Cryptogamie-Mycologie 33.

Montoya, P., Bandala, V.M., Haug, I., and Stubbe, D., 2012. A new species of Lactarius (subgenus Gerardii) from two relict Fagus grandifolia var. mexicana populations in Mexican montane cloud forests. Mycologia 104, 175-181.

Stubbe, D., Le Huyen, Wang, X.H., Nuytinck, J., Van de Putte, K., and Verbeken, A., 2012. The Australasian species of Lactarius subgenus Gerardii (Russulales). Fungal Diversity 52, 141-167.

Van den Bossche, D., De Bel, A., Hendrickx, M., De Becker, A., Jacobs, R., Naessens, A., and Piérard, D., 2012. Galactomannan Enzymatic Immunoassay Cross-Reactivity Caused by Prototheca Species. Journal of Clinical Microbiology 50, 3371-3373.

Stubbe, D. and Verbeken, A., 2012. Lactarius subg. Plinthogalus: The European taxa and American varieties of L. lignyotus re-evaluated. Mycologia 104, 1490-1501.

Packeu, A., Lebecque, P., Rodriguez-Villalobos, H., Boeras, A., Hendrickx, M., Bouchara, J.P., and Symoens, F., 2012. Molecular typing and antifungal susceptibility of Exophiala species isolates from patients with cystic fibrosis. J.Med Microbiol 61, 1226-1233.

Beguin, H., Pyck, N., Hendrickx, M., Planard, C., Stubbe, D., and Detandt, M., 2012. The taxonomic status of Trichophyton quinckeanum and T. interdigitale revisited: a multigene phylogenetic approach. Med Mycol 50, 871-882.

Hendrickx, M., Beguin, H., and Detandt, M., 2012. Genetic re-identification and antifungal susceptibility testing of Aspergillus section Nigri strains of the BCCM/IHEM collection. Mycoses 55, 148-155.

Van Rooij P., Declercq, J., and Beguin, H., 2012. Canine dermatophytosis caused by Trichophyton rubrum: an example of man-to-dog transmission. Mycoses 55, e15-e17.



Symoens, F., Jousson, O., Planard, C., Fratti, M., Staib, P., Mignon, B., and Monod, M., 2011. Molecular analysis and mating behaviour of the Trichophyton mentagrophytes species complex. Int J Med Microbiol 301, 260-266.

Hendrickx, M., Goffinet, J.S., Swinne, D., and Detandt, M., 2011. Screening of strains of the Candida parapsilosis group of the BCCM/IHEM collection by MALDI-TOF MS. Diagn Microbiol Infect Dis. 70, 544-548.


2000 – 2010

Jacobs, B., Pyck, N., and Smets, E., 2010. Phylogeny of the Linnaea clade: are Abelia and Zabelia closely related? Mol Phylogenet Evol 57, 741-752.

Swinne, D., Nolard, N., Van Rooij, P., and Detandt, M., 2009. Bloodstream yeast infections: a 15-month survey. Epidemiol Infect 137, 1037-1040.

Van Rooij P., Detandt, M., and Nolard, N., 2006. Trichophyton mentagrophytes of rabbit origin causing family incidence of kerion: an environmental study. Mycoses 49, 426-430.

Symoens, F., Willenz, P., Rouma, V., Planard, C., and Nolard, N., 1989. Isoelectric focusing applied to taxonomic differentiation of the Trichophyton mentagrophytes complex and the related Trichophyton interdigitale. Mycoses 32, 652-663.

Hagen, F., Illnait-Zaragozi, M.T., Bartlett, K.H., Swinne, D., Geertsen, E., Klaassen, C.H., Boekhout, T., and Meis, J.F., 2010. In vitro antifungal susceptibilities and amplified fragment length polymorphism genotyping of a worldwide collection of 350 clinical, veterinary, and environmental Cryptococcus gattii isolates. Antimicrob Agents Chemother 54, 5139-5145.

Swinne, D., Nolard, N., Van Rooij, P., and Detandt, M., 2009. Bloodstream yeast infections: a 15-month survey. Epidemiol Infect 137, 1037-1040.

Labriola, L., V B, Ercam, Swinne, D., and Jadoul, M., 2009. Successful treatment with voriconazole of prolonged Paecilomyces lilacinus fungemia in a chronic hemodialyzed patient. Clin Nephrol 71, 355-358.

Vervaeke, S., Vandamme, K., Boone, E., De Laere, E., Swinne, D., and Surmont, I., 2008. A case of Candida lambica fungemia misidentified as Candida krusei in an intravenous drug abuser. Med Mycol 46, 853-856.

Viviani, M.A., Cogliati, M., Esposto, M.C., Lemmer, K., Tintelnot, K., Colom Valiente, M.F., Swinne, D., Velegraki, A., and Velho, R., 2006. Molecular analysis of 311 Cryptococcus neoformans isolates from a 30-month ECMM survey of cryptococcosis in Europe. FEMS Yeast Res 6, 614-619.

Swinne, D., Watelle, M., and Nolard, N., 2005. In vitro activities of voriconazole, fluconazole, itraconazole and amphotericin B against non Candida albicans yeast isolates. Rev Iberoam Micol 22, 24-28.

Neyra, E., Fonteyne, P.A., Swinne, D., Fauche, F., Bustamante, B., and Nolard, N., 2005. Epidemiology of human sporotrichosis investigated by amplified fragment length polymorphism. J Clin Microbiol 43, 1348-1352.

Bauwens, L., Vercammen, F., Wuytack, C., Van Looveren, K., and Swinne, D., 2004. Isolation of Cryptococcus neoformans in Antwerp Zoo's nocturnal house
11. Mycoses 47, 292-296.

Swinne, D., Watelle, M., Suetens, C., Mertens, K., Fonteyne, P.A., and Nolard, N., 2004. A one-year survey of candidemia in Belgium in 2002. Epidemiol Infect 132, 1175-1180.

Bauters, T.G., Swinne, D., Stove, V., and Nelis, H.J., 2003. Detection of single cells of Cryptococcus neoformans in clinical samples by solid-phase cytometry
15. J Clin Microbiol . 41, 1736-1737.

Van Esbroeck M., Wuytack, C., Van Looveren, K., and Swinne, D., 2003. Isolation of Onychocola canadensis from four cases of onychomycosis in Belgium. Acta Clin Belg 58, 190-192.

Bauters, T.G., Swinne, D., Boekhout, T., Noens, L., and Nelis, H.J., 2002. Repeated isolation of Cryptococcus laurentii from the oropharynx of an immunocompromized patient
18. Mycopathologia 153, 133-135.

Martins-Nishikawa, M., Trilles, L., Symoens, F., Swinne, D., and Nolard, N., 2002. Prevalence of Candida dubliniensis in the BCCM/IHEM Biomedical Fungi/Yeasts culture collection (isolates before 1990). Med Mycol 40, 443-445.

De Baere, T., Claeys, G., Swinne, D., Verschraegen, G., Muylaert, A., Massonet, C., and Vaneechoutte, M., 2002. Identification of cultured isolates of clinically important yeast species using fluorescent fragment length analysis of the amplified internally transcribed rRNA spacer 2 region (ITS2). BMC Microbiol 2, 21.

Ostyn, B., Noe, A., Swinne, D., Ieven, M., and Colebunders, R., 2002. A multidrug, including voriconazole, resistant oral Candida infection in an AIDS patient effectively treated with echinocandin. J Infect 44, 57-58.

Swinne, D., Watelle, M., Van der Flaes, M., and Nolard, N., 2004. In vitro activities of voriconazole (UK-109, 496), fluconazole, itraconazole and amphotericin B against 132 non-albicans bloodstream yeast isolates (CANARI study). Mycoses 47, 177-183.

Chandenier, J., Adou-Bryn, K.D., Douchet, C., Sar, B., Kombila, M., Swinne, D., Therizol-Ferly, M., Buisson, Y., and Richard-Lenoble, D., 2004. In vitro activity of amphotericin B, fluconazole and voriconazole against 162 Cryptococcus neoformans isolates from Africa and Cambodia
13. Eur.J.Clin.Microbiol Infect Dis 23, 506-508.


Other articles

Tinea capitis is een niet te onderschatten probleem in de schoolgeneeskunde.
Detandt M, Van Rooij P, Planard C, Verstraeten C, Nolard N. 
Epidemiologisch bulletin van de Vlaamse
Gemeenschap,  2005, 52,  2, 8-12